Forget your poncey global warming, famine, war, tsunami, hurricane and asteriod collisions. In fact, lump them all together and it still wouldn't touch this.
If the methane bubble—a bubble that could be as big as 20 miles wide—erupts with titanic force from the seabed into the Gulf, every ship, drilling rig and structure within the region of the bubble will immediately sink. All the workers, engineers, Coast Guard personnel and marine biologists participating in the salvage operation will die instantly.
Better cash in your investments and enjoy them while you can!